Pam I'm not a doctor, so please take this for what it's worth. I've taken MTX for the last 2 + years, and I've been told by my Rheumy to stop taking MTX ,if I am on an antibiotic, and or running a fever.
And that's what I usually do, however if I'm not on antibiotics but can't seem to shake a chronic cold , I'll skip a week or so of MTX without consulting anyone, just so my body can get back to "normal"(whatever that is for "us" ) Doesn't happen very often.
If you still feel nervous about not taking the MTX , call your Pharamacist tomorrow (one day or even two days later is not going to matter)and ask his opinon, or wait til Mon. and call or pcp.
hope this helps,
Rosanne