Hi, I developed Cushings Syndrome after 4 years on Pred, all of the issues you mentioned, the buffalo hump, weight gain, I also developed Glaucoma and had to have laser surgery. I have been heading for diabetes with steroid induced syndrome X, but recntly decided on gastric sleeve surgery to help my own cause. After 12 years of steroids varying from 10 to 50mg daily, mainly 10mg, lots of steroid joint injections, immobility, steroid induced bone fractures that won't heal (in feet) I was warned that heart disease was a big big threat and the only thing I could do was lose weight if possible hence the op. I have now lost 32kg since October and I have stopped Chol, BP, heart rate, tabs and halved other drugs. I know I am still on the pred but my pain levels have changed and I am keen to start tapering to try and get to 7.5mg or 5mg preferrably in the future. Nobody ever tried to get me off of it even though it was causing many issues due to badly controlled RA permanently due to inability to use DMARDS and biologics. I can tolerate MTX on and off in between infections so that is my staple but can't get out of bed without steroids. I will be very interested to know how you go tapering as I would love to join you with that. hope this has been helpful and interesting to you. I also had steroid induced sleep apnoea and have not needed the machine now since weight loss thank God. Best of luck, Jane.